Frequency-domain wide-field laser Doppler in vivo imaging

We present a new instrument, based on a low-frame-rate 8Hz CCD camera used in a heterodyne opticalmixing configuration, that can create wide-field laser Doppler maps. As an illustration, we show results obtained in a mouse brain, in vivo, showing the Doppler signature of blood flow. The instrument is based on a frequency-shifting digital holography scheme.

© 2006 Optical Society of America